Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle

Nesprins, nuclear envelope spectrin-repeat proteins encoded by the SYNE1 and SYNE2 genes, are involved in localization of nuclei. The short isoform, nesprin-1-alpha2, is required for relocation of the microtubule organizer function from centromeres to the nuclear rim during myogenesis. Using specifi...

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Detalles Bibliográficos
Autores principales: Holt, Ian, Fuller, Heidi R., Lam, Le Thanh, Sewry, Caroline A., Shirran, Sally L., Zhang, Qiuping, Shanahan, Catherine M., Morris, Glenn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775114/
https://www.ncbi.nlm.nih.gov/pubmed/31578382
http://dx.doi.org/10.1038/s41598-019-50728-6

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