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Acquisition of a side population fraction augments malignant phenotype in ovarian cancer

Side population (SP) cells harbor malignant phenotypes in cancer. The aim of this study was to identify genes that modulate the proportion of ovarian cancer SP cells. Using a shRNA library targeting 15,000 genes, a functional genomics screen was performed to identify genes whose suppression increase...

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Detalles Bibliográficos
Autores principales: Yamanoi, Koji, Baba, Tsukasa, Abiko, Kaoru, Hamanishi, Junzo, Yamaguchi, Ken, Murakami, Ryusuke, Taki, Mana, Hosoe, Yuko, Murphy, Susan K., Konishi, Ikuo, Mandai, Masaki, Matsumura, Noriomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775117/
https://www.ncbi.nlm.nih.gov/pubmed/31578411
http://dx.doi.org/10.1038/s41598-019-50794-w