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Acquisition of a side population fraction augments malignant phenotype in ovarian cancer
Side population (SP) cells harbor malignant phenotypes in cancer. The aim of this study was to identify genes that modulate the proportion of ovarian cancer SP cells. Using a shRNA library targeting 15,000 genes, a functional genomics screen was performed to identify genes whose suppression increase...
Autores principales: | Yamanoi, Koji, Baba, Tsukasa, Abiko, Kaoru, Hamanishi, Junzo, Yamaguchi, Ken, Murakami, Ryusuke, Taki, Mana, Hosoe, Yuko, Murphy, Susan K., Konishi, Ikuo, Mandai, Masaki, Matsumura, Noriomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775117/ https://www.ncbi.nlm.nih.gov/pubmed/31578411 http://dx.doi.org/10.1038/s41598-019-50794-w |
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