Alkaline Phosphatase Treatment of Acute Kidney Injury in an Infant Piglet Model of Cardiopulmonary Bypass with Deep Hypothermic Circulatory Arrest

Acute kidney injury (AKI) is associated with prolonged hospitalization and mortality following infant cardiac surgery, but therapeutic options are limited. Alkaline phosphatase (AP) infusion reduced AKI in phase 2 sepsis trials but has not been evaluated for cardiac surgery-induced AKI. We developed...

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Detalles Bibliográficos
Autores principales: Davidson, Jesse A., Khailova, Ludmila, Treece, Amy, Robison, Justin, Soranno, Danielle E., Jaggers, James, Ing, Richard J., Lawson, Scott, Lujan, Suzanne Osorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775126/
https://www.ncbi.nlm.nih.gov/pubmed/31578351
http://dx.doi.org/10.1038/s41598-019-50481-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775126/
https://www.ncbi.nlm.nih.gov/pubmed/31578351
http://dx.doi.org/10.1038/s41598-019-50481-w

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