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A Framework for Annotation of Antigen Specificities in High-Throughput T-Cell Repertoire Sequencing Studies
Recently developed molecular methods allow large-scale profiling of T-cell receptor (TCR) sequences that encode for antigen specificity and immunological memory of these cells. However, it is well-known that the even unperturbed TCR repertoire structure is extremely complex due to the high diversity...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775185/ https://www.ncbi.nlm.nih.gov/pubmed/31616409 http://dx.doi.org/10.3389/fimmu.2019.02159 |