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Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice

Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited due to poorly developed follicular dendritic cells (FDC), causing generation of few antibody-secreting cells (ASCs) with limited survival and transient antibody responses....

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Detalles Bibliográficos
Autores principales:	Aradottir Pind, Audur Anna, Dubik, Magdalena, Thorsdottir, Sigrun, Meinke, Andreas, Harandi, Ali M., Holmgren, Jan, Del Giudice, Giuseppe, Jonsdottir, Ingileif, Bjarnarson, Stefania P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775194/ https://www.ncbi.nlm.nih.gov/pubmed/31616417 http://dx.doi.org/10.3389/fimmu.2019.02214

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