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The Impact of CYP3A4*22 on Tacrolimus Pharmacokinetics and Outcome in Clinical Practice at a Single Kidney Transplant Center

Background: Although there is evidence that the CYP3A4*22 variant should be considered in tacrolimus dosing in renal transplantation, its impact beyond tacrolimus dose requirements remains controversial. Methods: In a cohort of 121 kidney transplant recipients, we analyzed the CYP3A4*1B, CYP3A4*22,...

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Detalles Bibliográficos
Autores principales:	Abdel-Kahaar, Emaad, Winter, Stefan, Tremmel, Roman, Schaeffeler, Elke, Olbricht, Christoph J., Wieland, Eberhard, Schwab, Matthias, Shipkova, Maria, Jaeger, Simon U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775237/ https://www.ncbi.nlm.nih.gov/pubmed/31616470 http://dx.doi.org/10.3389/fgene.2019.00871

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