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P21 and P27 promote tumorigenesis and progression via cell cycle acceleration in seminal vesicles of TRAMP mice

Transgenic adenocarcinoma mouse prostate (TRAMP) model is established to mimic human prostate cancer progression, where seminal vesicle lesions often occur and has been described as phyllodes-like epithelial-stromal tumors. However, the molecular mechanism regulating tumorigenesis and progression in...

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Detalles Bibliográficos
Autores principales: Li, Tonghui, Wang, Fangfang, Dang, Yanmei, Dong, Jiajie, Zhang, Yu, Zhang, Chi, Liu, Ping, Gao, Yanhong, Wang, Xiaojun, Yang, Sijun, Lu, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775302/
https://www.ncbi.nlm.nih.gov/pubmed/31592235
http://dx.doi.org/10.7150/ijbs.35092