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Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study

This study presents the postoperative pregnancy rate of women with recurrent endometriosis and evaluates the predictive value of the endometriosis fertility index (EFI) for the pregnancy. A total of 107 women who wished to conceive after surgery for recurrent endometriosis from January 2007 to Decem...

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Autores principales: Zhou, Yong, Lin, Li, Chen, Zhengyun, Wang, Yuan, Chen, Chaolu, Li, Enchun, Wu, Ruijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775358/
https://www.ncbi.nlm.nih.gov/pubmed/31574795
http://dx.doi.org/10.1097/MD.0000000000016965
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author Zhou, Yong
Lin, Li
Chen, Zhengyun
Wang, Yuan
Chen, Chaolu
Li, Enchun
Wu, Ruijin
author_facet Zhou, Yong
Lin, Li
Chen, Zhengyun
Wang, Yuan
Chen, Chaolu
Li, Enchun
Wu, Ruijin
author_sort Zhou, Yong
collection PubMed
description This study presents the postoperative pregnancy rate of women with recurrent endometriosis and evaluates the predictive value of the endometriosis fertility index (EFI) for the pregnancy. A total of 107 women who wished to conceive after surgery for recurrent endometriosis from January 2007 to December 2016 were included. The EFI score was calculated postoperatively. The receiver operator characteristic (ROC) curve was plotted to determine the most promising contributor to predicting pregnancy, and Kaplan–Meier (K–M) analysis was used to estimate the cumulative pregnancy rate (CPR). A total of 61 pregnancies were registered in 58 women and the remaining 49 patients failed to become pregnant. The EFI score was strongly associated with the postoperative fertility prognosis. The CPRs during the first 2 and 3 years postoperatively were 51.86% and 66.38%, respectively, and increased to 71.98% within the first 5 years postoperatively in patients with EFI scores ≥5. However, the CPR was 26.00% during the first 2 years after surgery in individuals with EFI scores <5, and there was no increase in the CRP thereafter. Women suffering from recurrent endometriosis still experienced a probability of natural pregnancy, especially patients with EFI scores ≥5. The EFI score had good predictive power for postoperative pregnancy in these patients.
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spelling pubmed-67753582019-10-07 Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study Zhou, Yong Lin, Li Chen, Zhengyun Wang, Yuan Chen, Chaolu Li, Enchun Wu, Ruijin Medicine (Baltimore) 5600 This study presents the postoperative pregnancy rate of women with recurrent endometriosis and evaluates the predictive value of the endometriosis fertility index (EFI) for the pregnancy. A total of 107 women who wished to conceive after surgery for recurrent endometriosis from January 2007 to December 2016 were included. The EFI score was calculated postoperatively. The receiver operator characteristic (ROC) curve was plotted to determine the most promising contributor to predicting pregnancy, and Kaplan–Meier (K–M) analysis was used to estimate the cumulative pregnancy rate (CPR). A total of 61 pregnancies were registered in 58 women and the remaining 49 patients failed to become pregnant. The EFI score was strongly associated with the postoperative fertility prognosis. The CPRs during the first 2 and 3 years postoperatively were 51.86% and 66.38%, respectively, and increased to 71.98% within the first 5 years postoperatively in patients with EFI scores ≥5. However, the CPR was 26.00% during the first 2 years after surgery in individuals with EFI scores <5, and there was no increase in the CRP thereafter. Women suffering from recurrent endometriosis still experienced a probability of natural pregnancy, especially patients with EFI scores ≥5. The EFI score had good predictive power for postoperative pregnancy in these patients. Wolters Kluwer Health 2019-09-27 /pmc/articles/PMC6775358/ /pubmed/31574795 http://dx.doi.org/10.1097/MD.0000000000016965 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 5600
Zhou, Yong
Lin, Li
Chen, Zhengyun
Wang, Yuan
Chen, Chaolu
Li, Enchun
Wu, Ruijin
Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study
title Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study
title_full Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study
title_fullStr Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study
title_full_unstemmed Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study
title_short Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study
title_sort fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: a retrospective study
topic 5600
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775358/
https://www.ncbi.nlm.nih.gov/pubmed/31574795
http://dx.doi.org/10.1097/MD.0000000000016965
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