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Epigenetic Suppression of Interferon Lambda Receptor Expression Leads to Enhanced Human Norovirus Replication In Vitro

Human norovirus (HuNoV) is the main cause of gastroenteritis worldwide, yet no therapeutics are currently available. Here, we utilize a human norovirus replicon in human gastric tumor (HGT) cells to identify host factors involved in promoting or inhibiting HuNoV replication. We observed that an inte...

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Detalles Bibliográficos
Autores principales:	Arthur, Sabastine E., Sorgeloos, Frédéric, Hosmillo, Myra, Goodfellow, Ian G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775457/ https://www.ncbi.nlm.nih.gov/pubmed/31575769 http://dx.doi.org/10.1128/mBio.02155-19

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