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Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers

HIV-exposed uninfected infants (HEU) represent a growing population in developing countries including Gabon. Several studies have shown the vulnerability of these infants toward infectious diseases. The aim of the study was to contribute to the global effort to understand how HIVexposure or anti ret...

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Autores principales: Siawaya, Anicet Christel Maloupazoa, Mveang-Nzoghe, Amandine, Mpega, Chérone Nancy Mbani, Leboueny, Marielle, Ndjindji, Ofilia Mvoundza, Ndong, Armel Mintsa, Essone, Paulin N., Siawaya, Joel Fleury Djoba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775485/
https://www.ncbi.nlm.nih.gov/pubmed/31583065
http://dx.doi.org/10.4081/hr.2019.7056
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author Siawaya, Anicet Christel Maloupazoa
Mveang-Nzoghe, Amandine
Mpega, Chérone Nancy Mbani
Leboueny, Marielle
Ndjindji, Ofilia Mvoundza
Ndong, Armel Mintsa
Essone, Paulin N.
Siawaya, Joel Fleury Djoba
author_facet Siawaya, Anicet Christel Maloupazoa
Mveang-Nzoghe, Amandine
Mpega, Chérone Nancy Mbani
Leboueny, Marielle
Ndjindji, Ofilia Mvoundza
Ndong, Armel Mintsa
Essone, Paulin N.
Siawaya, Joel Fleury Djoba
author_sort Siawaya, Anicet Christel Maloupazoa
collection PubMed
description HIV-exposed uninfected infants (HEU) represent a growing population in developing countries including Gabon. Several studies have shown the vulnerability of these infants toward infectious diseases. The aim of the study was to contribute to the global effort to understand how HIVexposure or anti retroviral therapy affects infants’ blood elements. We assessed HEU infants’ complete blood count using a blood analyzer instrument. Our investigations showed that among the observed clinically relevant hematological abnormalities events, thrombocytosis was the most prevalent clinically relevant hematological abnormality associated with HEU infants’. We showed that HEU infants had significantly higher platelets count than HUinfants. Therefore, higher level of platelets seems to characterize HEU infants when compared to HU infants.
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spelling pubmed-67754852019-10-03 Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers Siawaya, Anicet Christel Maloupazoa Mveang-Nzoghe, Amandine Mpega, Chérone Nancy Mbani Leboueny, Marielle Ndjindji, Ofilia Mvoundza Ndong, Armel Mintsa Essone, Paulin N. Siawaya, Joel Fleury Djoba Hematol Rep Brief Report HIV-exposed uninfected infants (HEU) represent a growing population in developing countries including Gabon. Several studies have shown the vulnerability of these infants toward infectious diseases. The aim of the study was to contribute to the global effort to understand how HIVexposure or anti retroviral therapy affects infants’ blood elements. We assessed HEU infants’ complete blood count using a blood analyzer instrument. Our investigations showed that among the observed clinically relevant hematological abnormalities events, thrombocytosis was the most prevalent clinically relevant hematological abnormality associated with HEU infants’. We showed that HEU infants had significantly higher platelets count than HUinfants. Therefore, higher level of platelets seems to characterize HEU infants when compared to HU infants. PAGEPress Publications, Pavia, Italy 2019-09-27 /pmc/articles/PMC6775485/ /pubmed/31583065 http://dx.doi.org/10.4081/hr.2019.7056 Text en ©Copyright: the Author(s), 2019 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Siawaya, Anicet Christel Maloupazoa
Mveang-Nzoghe, Amandine
Mpega, Chérone Nancy Mbani
Leboueny, Marielle
Ndjindji, Ofilia Mvoundza
Ndong, Armel Mintsa
Essone, Paulin N.
Siawaya, Joel Fleury Djoba
Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers
title Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers
title_full Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers
title_fullStr Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers
title_full_unstemmed Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers
title_short Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers
title_sort increased platelets count in hiv-1 uninfected infants born from hiv-1 infected mothers
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775485/
https://www.ncbi.nlm.nih.gov/pubmed/31583065
http://dx.doi.org/10.4081/hr.2019.7056
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