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Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers
HIV-exposed uninfected infants (HEU) represent a growing population in developing countries including Gabon. Several studies have shown the vulnerability of these infants toward infectious diseases. The aim of the study was to contribute to the global effort to understand how HIVexposure or anti ret...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775485/ https://www.ncbi.nlm.nih.gov/pubmed/31583065 http://dx.doi.org/10.4081/hr.2019.7056 |
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author | Siawaya, Anicet Christel Maloupazoa Mveang-Nzoghe, Amandine Mpega, Chérone Nancy Mbani Leboueny, Marielle Ndjindji, Ofilia Mvoundza Ndong, Armel Mintsa Essone, Paulin N. Siawaya, Joel Fleury Djoba |
author_facet | Siawaya, Anicet Christel Maloupazoa Mveang-Nzoghe, Amandine Mpega, Chérone Nancy Mbani Leboueny, Marielle Ndjindji, Ofilia Mvoundza Ndong, Armel Mintsa Essone, Paulin N. Siawaya, Joel Fleury Djoba |
author_sort | Siawaya, Anicet Christel Maloupazoa |
collection | PubMed |
description | HIV-exposed uninfected infants (HEU) represent a growing population in developing countries including Gabon. Several studies have shown the vulnerability of these infants toward infectious diseases. The aim of the study was to contribute to the global effort to understand how HIVexposure or anti retroviral therapy affects infants’ blood elements. We assessed HEU infants’ complete blood count using a blood analyzer instrument. Our investigations showed that among the observed clinically relevant hematological abnormalities events, thrombocytosis was the most prevalent clinically relevant hematological abnormality associated with HEU infants’. We showed that HEU infants had significantly higher platelets count than HUinfants. Therefore, higher level of platelets seems to characterize HEU infants when compared to HU infants. |
format | Online Article Text |
id | pubmed-6775485 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-67754852019-10-03 Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers Siawaya, Anicet Christel Maloupazoa Mveang-Nzoghe, Amandine Mpega, Chérone Nancy Mbani Leboueny, Marielle Ndjindji, Ofilia Mvoundza Ndong, Armel Mintsa Essone, Paulin N. Siawaya, Joel Fleury Djoba Hematol Rep Brief Report HIV-exposed uninfected infants (HEU) represent a growing population in developing countries including Gabon. Several studies have shown the vulnerability of these infants toward infectious diseases. The aim of the study was to contribute to the global effort to understand how HIVexposure or anti retroviral therapy affects infants’ blood elements. We assessed HEU infants’ complete blood count using a blood analyzer instrument. Our investigations showed that among the observed clinically relevant hematological abnormalities events, thrombocytosis was the most prevalent clinically relevant hematological abnormality associated with HEU infants’. We showed that HEU infants had significantly higher platelets count than HUinfants. Therefore, higher level of platelets seems to characterize HEU infants when compared to HU infants. PAGEPress Publications, Pavia, Italy 2019-09-27 /pmc/articles/PMC6775485/ /pubmed/31583065 http://dx.doi.org/10.4081/hr.2019.7056 Text en ©Copyright: the Author(s), 2019 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Report Siawaya, Anicet Christel Maloupazoa Mveang-Nzoghe, Amandine Mpega, Chérone Nancy Mbani Leboueny, Marielle Ndjindji, Ofilia Mvoundza Ndong, Armel Mintsa Essone, Paulin N. Siawaya, Joel Fleury Djoba Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers |
title | Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers |
title_full | Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers |
title_fullStr | Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers |
title_full_unstemmed | Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers |
title_short | Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers |
title_sort | increased platelets count in hiv-1 uninfected infants born from hiv-1 infected mothers |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775485/ https://www.ncbi.nlm.nih.gov/pubmed/31583065 http://dx.doi.org/10.4081/hr.2019.7056 |
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