Cargando…

Saikosaponin-d Increases the Radiosensitivity of Hepatoma Cells by Adjusting Cell Autophagy

Radiotherapy for liver cancer can affect the level of autophagy in cells, and effective autophagy regulation can increase the radiosensitivity of liver cancer cells.Saikosaponin-d (SSd) is an effective active ingredient extracted from traditional Chinese medicine Bupleurum. We have confirmed previou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Yin-Di, Lin, Shuai, Yang, Peng-Tao, Bai, Ming-Hua, Jin, Ying-Ying, Min, Wei-Li, Ma, Hong-Bing, Wang, Bao-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775525/ https://www.ncbi.nlm.nih.gov/pubmed/31598167 http://dx.doi.org/10.7150/jca.30286

Ejemplares similares

Saikosaponin-d increases the radiosensitivity of smmc-7721 hepatocellular carcinoma cells by adjusting the g0/g1 and g2/m checkpoints of the cell cycle
por: Wang, Bao-Feng, et al.
Publicado: (2013)

Saikosaponin-d increases radiation-induced apoptosis of hepatoma cells by promoting autophagy via inhibiting mTOR phosphorylation
por: Wang, Baofeng, et al.
Publicado: (2021)

Saikosaponin D suppresses enterovirus A71 infection by inhibiting autophagy
por: Li, Chang, et al.
Publicado: (2019)

Untargeted Metabolomics Study of the In Vitro Anti-Hepatoma Effect of Saikosaponin d in Combination with NRP-1 Knockdown
por: Lv, Yingtong, et al.
Publicado: (2019)

Antitumor Effect of Saikosaponin A on Human Neuroblastoma Cells
por: Cheng, Tan, et al.
Publicado: (2021)

Saikosaponin-d Inhibits the Hepatoma Cells and Enhances Chemosensitivity Through SENP5-Dependent Inhibition of Gli1 SUMOylation Under Hypoxia
por: Zhang, Chun-Yan, et al.
Publicado: (2019)

DHX15 Inhibits Autophagy and the Proliferation of Hepatoma Cells
por: Zhao, Miaomiao, et al.
Publicado: (2021)

Formulations, Hemolytic and Pharmacokinetic Studies on Saikosaponin a and Saikosaponin d Compound Liposomes
por: Zhang, Guo-Song, et al.
Publicado: (2015)

SMC4 enhances the chemoresistance of hepatoma cells by promoting autophagy
por: Zhang, Shi-Ran, et al.
Publicado: (2022)

Effects of SSd Combined with Radiation on Inhibiting SMMC-7721 Hepatoma Cell Growth
por: Wang, Bao-feng, et al.
Publicado: (2014)

Facile Synthesis of Saikosaponins
por: Wang, Ziqiang, et al.
Publicado: (2021)

Uncoupling Protein 2 Regulates Palmitic Acid-Induced Hepatoma Cell Autophagy
por: Lou, Jiaxin, et al.
Publicado: (2014)

Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity
por: von Fallois, Moritz, et al.
Publicado: (2021)

Saikosaponin-d affects the differentiation, maturation and function of monocyte-derived dendritic cells
por: YING, ZUO-LIN, et al.
Publicado: (2014)

Reparative and toxicity-reducing effects of liposome-encapsulated saikosaponin in mice with liver fibrosis
por: Shiu, Li-Yen, et al.
Publicado: (2020)

Saikosaponin D inhibits autophagosome-lysosome fusion and induces autophagy-independent apoptosis in MDA-MB-231 breast cancer cells
por: Fu, Ruoqiu, et al.
Publicado: (2020)

Saikosaponin-d alleviates hepatic fibrosis through regulating GPER1/autophagy signaling
por: Chen, Yirong, et al.
Publicado: (2021)

Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma
por: Liu, Guimei, et al.
Publicado: (2022)

Polydatin Increases Radiosensitivity by Inducing Apoptosis of Stem Cells in Colorectal Cancer
por: Chen, Qiu, et al.
Publicado: (2019)

Autophagy and radiosensitization in cancer
por: Sharma, Khushboo, et al.
Publicado: (2014)

Upregulation of microRNA-98 increases radiosensitivity in esophageal squamous cell carcinoma
por: Jin, Ying-Ying, et al.
Publicado: (2016)

Overexpression of BcERF3 increases the biosynthesis of saikosaponins in Bupleurum chinense
por: Han, Wenjing, et al.
Publicado: (2022)

Saikosaponin D attenuates inflammatory response and cell apoptosis of lipopolysaccharide‐induced lung epithelial cells
por: Song, Lijie, et al.
Publicado: (2023)

Autophagy inhibition enhances radiosensitivity of Eca-109 cells via the mitochondrial apoptosis pathway
por: Tao, Hua, et al.
Publicado: (2018)

Purposing Saikosaponins for the treatment of COVID-19
por: Bahbah, Eshak I., et al.
Publicado: (2020)

Increasing radiosensitivity with the downregulation of cofilin-1 in U251 human glioma cells
por: DU, HUA-QING, et al.
Publicado: (2015)

Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells
por: Zhou, Weipeng, et al.
Publicado: (2020)

Cordycepin Enhances Radiosensitivity in Oral Squamous Carcinoma Cells by Inducing Autophagy and Apoptosis Through Cell Cycle Arrest
por: Ho, Sheng-Yow, et al.
Publicado: (2019)

Saikosaponin a increases interleukin-10 expression and inhibits scar formation after sciatic nerve injury
por: Huang, Meng-Qiang, et al.
Publicado: (2018)

Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin
por: Chang, Wen-Tsan, et al.
Publicado: (2014)

Sinomenine hydrochloride inhibits cell survival in human hepatoma Huh7 cells
por: Wang, Ying, et al.
Publicado: (2018)

Chemotherapeutic Potential of Saikosaponin D: Experimental Evidence
por: Manoharan, Suryaa, et al.
Publicado: (2022)

Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins
por: Sui, Chun, et al.
Publicado: (2011)

Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis
por: Ye, Hongxing, et al.
Publicado: (2016)

Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells
por: Wang, Qiong, et al.
Publicado: (2010)

A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applications
por: Yuan, Bochuan, et al.
Publicado: (2016)

Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells
por: Wong, Vincent Kam Wai, et al.
Publicado: (2013)

LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy
por: Chu, Chu, et al.
Publicado: (2019)

The synergistic radiosensitizing effect of tirapazamine-conjugated gold nanoparticles on human hepatoma HepG2 cells under X-ray irradiation
por: Liu, Xi, et al.
Publicado: (2016)

Suppression of autophagy by mycophenolic acid contributes to inhibition of HCV replication in human hepatoma cells
por: Fang, Shoucai, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_qsogq28v5mbph5c3oh6322g7d7