Comprehensive biomarker analyses identifies HER2, EGFR, MET RNA expression and thymidylate synthase 5'UTR SNP as predictors of benefit from S-1 adjuvant chemotherapy in Japanese patients with stage II/III gastric cancer

Purpose: A comprehensive molecular analysis was conducted to identify prognostic and predictive markers for adjuvant S-1 chemotherapy in stage II/III Japanese gastric cancer (GC) patients and to evaluate their potential suitability for alternative cytotoxic or targeted drugs. Experimental Design: We...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Takaki, Aoyama, Toru, Sakamaki, Kentaro, Oshima, Takasi, Lin, Joyce, Zhang, Shenli, Sapari, Nur Sabrina, Soong, Richie, Tan, Iain, Chan, Xiu Bin, Bottomley, Dan, Hewitt, Lindsay C, Arai, Tomio, Teh, Bin Tean, Epstein, David, Ogata, Takashi, Kameda, Yoichi, Miyagi, Yohei, Tsuburaya, Akira, Morita, Satoshi, Grabsch, Heike I, Tan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775596/
https://www.ncbi.nlm.nih.gov/pubmed/31602266
http://dx.doi.org/10.7150/jca.34741

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