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Update on current pancreatic treatments: from molecular pathways to treatment

Pancreatic cancer is still diagnosed at a late stage although we have novel diagnostic tools. Pancreatic cancer chemotherapy treatment resistance is observed and therefore novel treatments are in need. Anti-cancer stem cell therapy, combination of chemotherapy and/or radiotherapy with immunotherapy,...

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Autores principales: Sapalidis, Konstantinos, Kosmidis, Christoforos, Funtanidou, Varvara, Katsaounis, Athanasios, Barmpas, Amastasios, Koimtzis, Georgios, Mantalobas, Stylianos, Alexandrou, Vyron, Aidoni, Zoi, Koulouris, Charilaos, Pavlidis, Efstathios, Giannakidis, Dimitrios, Surlin, Valeriu, Pantea, Stelian, Strambu, Victor, Constantina, Rogoveanu Otilia, Amaniti, Aikaterini, Zarogoulidis, Paul, Mogoantă, Stelian, Kesisoglou, Isaak, Sardeli, Chrysanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775621/
https://www.ncbi.nlm.nih.gov/pubmed/31602269
http://dx.doi.org/10.7150/jca.36300
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author Sapalidis, Konstantinos
Kosmidis, Christoforos
Funtanidou, Varvara
Katsaounis, Athanasios
Barmpas, Amastasios
Koimtzis, Georgios
Mantalobas, Stylianos
Alexandrou, Vyron
Aidoni, Zoi
Koulouris, Charilaos
Pavlidis, Efstathios
Giannakidis, Dimitrios
Surlin, Valeriu
Pantea, Stelian
Strambu, Victor
Constantina, Rogoveanu Otilia
Amaniti, Aikaterini
Zarogoulidis, Paul
Mogoantă, Stelian
Kesisoglou, Isaak
Sardeli, Chrysanthi
author_facet Sapalidis, Konstantinos
Kosmidis, Christoforos
Funtanidou, Varvara
Katsaounis, Athanasios
Barmpas, Amastasios
Koimtzis, Georgios
Mantalobas, Stylianos
Alexandrou, Vyron
Aidoni, Zoi
Koulouris, Charilaos
Pavlidis, Efstathios
Giannakidis, Dimitrios
Surlin, Valeriu
Pantea, Stelian
Strambu, Victor
Constantina, Rogoveanu Otilia
Amaniti, Aikaterini
Zarogoulidis, Paul
Mogoantă, Stelian
Kesisoglou, Isaak
Sardeli, Chrysanthi
author_sort Sapalidis, Konstantinos
collection PubMed
description Pancreatic cancer is still diagnosed at a late stage although we have novel diagnostic tools. Pancreatic cancer chemotherapy treatment resistance is observed and therefore novel treatments are in need. Anti-cancer stem cell therapy, combination of chemotherapy and/or radiotherapy with immunotherapy, proteins/enzymes and gene therapy are currently under evaluation. Targeted treatment with tyrosine kinase inhibitors is also administered and novel inhibitors are also under evaluation. In the current review we present recent data from our search within the year 2018.
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spelling pubmed-67756212019-10-10 Update on current pancreatic treatments: from molecular pathways to treatment Sapalidis, Konstantinos Kosmidis, Christoforos Funtanidou, Varvara Katsaounis, Athanasios Barmpas, Amastasios Koimtzis, Georgios Mantalobas, Stylianos Alexandrou, Vyron Aidoni, Zoi Koulouris, Charilaos Pavlidis, Efstathios Giannakidis, Dimitrios Surlin, Valeriu Pantea, Stelian Strambu, Victor Constantina, Rogoveanu Otilia Amaniti, Aikaterini Zarogoulidis, Paul Mogoantă, Stelian Kesisoglou, Isaak Sardeli, Chrysanthi J Cancer Review Pancreatic cancer is still diagnosed at a late stage although we have novel diagnostic tools. Pancreatic cancer chemotherapy treatment resistance is observed and therefore novel treatments are in need. Anti-cancer stem cell therapy, combination of chemotherapy and/or radiotherapy with immunotherapy, proteins/enzymes and gene therapy are currently under evaluation. Targeted treatment with tyrosine kinase inhibitors is also administered and novel inhibitors are also under evaluation. In the current review we present recent data from our search within the year 2018. Ivyspring International Publisher 2019-08-28 /pmc/articles/PMC6775621/ /pubmed/31602269 http://dx.doi.org/10.7150/jca.36300 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Sapalidis, Konstantinos
Kosmidis, Christoforos
Funtanidou, Varvara
Katsaounis, Athanasios
Barmpas, Amastasios
Koimtzis, Georgios
Mantalobas, Stylianos
Alexandrou, Vyron
Aidoni, Zoi
Koulouris, Charilaos
Pavlidis, Efstathios
Giannakidis, Dimitrios
Surlin, Valeriu
Pantea, Stelian
Strambu, Victor
Constantina, Rogoveanu Otilia
Amaniti, Aikaterini
Zarogoulidis, Paul
Mogoantă, Stelian
Kesisoglou, Isaak
Sardeli, Chrysanthi
Update on current pancreatic treatments: from molecular pathways to treatment
title Update on current pancreatic treatments: from molecular pathways to treatment
title_full Update on current pancreatic treatments: from molecular pathways to treatment
title_fullStr Update on current pancreatic treatments: from molecular pathways to treatment
title_full_unstemmed Update on current pancreatic treatments: from molecular pathways to treatment
title_short Update on current pancreatic treatments: from molecular pathways to treatment
title_sort update on current pancreatic treatments: from molecular pathways to treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775621/
https://www.ncbi.nlm.nih.gov/pubmed/31602269
http://dx.doi.org/10.7150/jca.36300
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