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Associations of PGK1 promoter hypomethylation and PGK1-mediated PDHK1 phosphorylation with cancer stage and prognosis: a TCGA pan-cancer analysis

BACKGROUND: Cancer cells reprogram metabolism for proliferation. Phosphoglycerate kinase 1 (PGK1), as a glycolytic enzyme and newly identified protein kinase, coordinates glycolysis and mitochondrial metabolism. However, the clinical significance of PGK1 expression and function in cancer progression...

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Detalles Bibliográficos
Autores principales:	Shao, Fei, Yang, Xueying, Wang, Wei, Wang, Juhong, Guo, Wei, Feng, Xiaoli, Shi, Susheng, Xue, Qi, Gao, Shugeng, Gao, Yibo, Lu, Zhimin, He, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775656/ https://www.ncbi.nlm.nih.gov/pubmed/31578148 http://dx.doi.org/10.1186/s40880-019-0401-9

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