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Crystal structure of (1S,2R)-2-[(3R,4S)-3-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-2-yl]-1,2-diphenylethanol
The synthesis and crystal structure of the title compound, C(30)H(29)NO, are described. This compound is a member of the chiral dihydroisoquinoline-derived family, used as building blocks for functional materials and as source of chirality in asymmetric synthesis, and was isolated as one of two d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775741/ https://www.ncbi.nlm.nih.gov/pubmed/31636965 http://dx.doi.org/10.1107/S2056989019011964 |
Sumario: | The synthesis and crystal structure of the title compound, C(30)H(29)NO, are described. This compound is a member of the chiral dihydroisoquinoline-derived family, used as building blocks for functional materials and as source of chirality in asymmetric synthesis, and was isolated as one of two diastereomeric β-amino alcohols, the title molecule being found to be the (S,R) diastereoisomer. In the crystal, molecules are packed in a herringbone manner parallel to (103) and (10[Image: see text]) via weak C—H⋯O and C—H⋯π(ring) interactions. Hirshfeld surface analysis showed that the surface contacts are predominantly H⋯H interactions (ca 75%). The crystal studied was refined as a two-component inversion twin. |
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