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Effects of Bone Marrow-Derived Mesenchymal Stem Cells on Hypoxia and the Transforming Growth Factor beta 1 (TGFβ-1) and SMADs Pathway in a Mouse Model of Cirrhosis

BACKGROUND: The role of bone marrow-derived mesenchymal stem cells (BM-MSCs) in liver fibrosis remains poorly understood. This study aimed to use a mouse model of carbon tetrachloride (CCL(4))-induced liver fibrosis to investigate the effects of BM-MSCs during liver hypoxia and the involvement of th...

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Detalles Bibliográficos
Autores principales: Zhang, Liting, Zhou, Dan, Li, Junfeng, Yan, Xiaoming, Zhu, Jun, Xiao, Ping, Chen, Tuo, Xie, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775794/
https://www.ncbi.nlm.nih.gov/pubmed/31550244
http://dx.doi.org/10.12659/MSM.916428