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Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer

The influenza A virus RNA-dependent RNA polymerase complex consists in three subunits, PB2, PB1 and PA, that perform transcription and replication of the viral genome through very distinct mechanisms. Biochemical and structural studies have revealed that the polymerase can adopt multiple conformatio...

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Detalles Bibliográficos
Autores principales:	Chen, Kuang-Yu, Santos Afonso, Emmanuel Dos, Enouf, Vincent, Isel, Catherine, Naffakh, Nadia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776259/ https://www.ncbi.nlm.nih.gov/pubmed/31581279 http://dx.doi.org/10.1371/journal.ppat.1008034

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