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eQTL mapping of rare variant associations using RNA-seq data: An evaluation of approaches
Expression quantitative trait loci (eQTL) provide insight on transcription regulation and illuminate the molecular basis of phenotypic outcomes. High-throughput RNA sequencing (RNA-seq) is becoming a popular technique to measure gene expression abundance. Traditional eQTL mapping methods for microar...
Autores principales: | Lutz, Sharon Marie, Thwing, Annie, Fingerlin, Tasha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776318/ https://www.ncbi.nlm.nih.gov/pubmed/31581212 http://dx.doi.org/10.1371/journal.pone.0223273 |
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