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Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process
Alternative splicing diversifies mRNA transcripts in human cells. While the spliceosome pairs exons with a high degree of accuracy, the rates of rare aberrant and non-canonical pre-mRNA splicing have not been evaluated at the nucleotide level to determine the quantity and identity of these events ac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776343/ https://www.ncbi.nlm.nih.gov/pubmed/31581208 http://dx.doi.org/10.1371/journal.pone.0223132 |