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Pregnane X receptor activation constrains mucosal NF-κB activity in active inflammatory bowel disease

BACKGROUND: The Pregnane X Receptor (PXR) is a principal signal transducer in mucosal responses to xenobiotic stress. It is well-recognized that inflammatory bowel disease is accompanied by xenobiotic stress, but the importance of the PXR in limiting inflammatory responses in inflammatory bowel dise...

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Detalles Bibliográficos
Autores principales:	Deuring, J. Jasper, Li, Meng, Cao, Wanlu, Chen, Sunrui, Wang, Wenshi, de Haar, Colin, van der Woude, C. Janneke, Peppelenbosch, Maikel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776398/ https://www.ncbi.nlm.nih.gov/pubmed/31581194 http://dx.doi.org/10.1371/journal.pone.0221924

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