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Lobaplatin promotes (125)I-induced apoptosis and inhibition of proliferation in hepatocellular carcinoma by upregulating PERK-eIF2α-ATF4-CHOP pathway

We investigated the mechanism underlying the effect of a combination treatment of (125)I radioactive seed implantation and lobaplatin (LBP) in hepatocellular carcinoma. The effects of administration of HCC cells and subcutaneous tumor model of mice with different doses of (125)I or a sensitizing con...

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Detalles Bibliográficos
Autores principales: Li, Dong, Wang, Wu-jie, Wang, Yong-zheng, Wang, Yi-biao, Li, Yu-liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776519/
https://www.ncbi.nlm.nih.gov/pubmed/31582720
http://dx.doi.org/10.1038/s41419-019-1918-1

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