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DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: a prospective analysis

The stress response system is disrupted in individuals with major depressive disorder (MDD) as well as in those at elevated risk for developing MDD. We examined whether DNA methylation (DNAm) levels of CpG sites within HPA-axis genes predict the onset of MDD. Seventy-seven girls, approximately half...

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Detalles Bibliográficos
Autores principales: Humphreys, Kathryn L., Moore, Sarah R., Davis, Elena Goetz, MacIsaac, Julie L., Lin, David T. S., Kobor, Michael S., Gotlib, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776528/
https://www.ncbi.nlm.nih.gov/pubmed/31582756
http://dx.doi.org/10.1038/s41398-019-0582-7