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The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53

Desmoglein-3 (Dsg3), the Pemphigus Vulgaris (PV) antigen (PVA), plays an essential role in keratinocyte cell–cell adhesion and regulates various signaling pathways involved in the progression and metastasis of cancer where it is upregulated. We show here that expression of Dsg3 impacts on the expres...

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Detalles Bibliográficos
Autores principales: Rehman, Ambreen, Cai, Yang, Hünefeld, Christian, Jedličková, Hana, Huang, Yunying, Teck Teh, Muy, Sharif Ahmad, Usama, Uttagomol, Jutamas, Wang, Ying, Kang, Angray, Warnes, Gary, Harwood, Catherine, Bergamaschi, Daniele, Kenneth Parkinson, Eric, Röcken, Martin, Wan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776551/
https://www.ncbi.nlm.nih.gov/pubmed/31582719
http://dx.doi.org/10.1038/s41419-019-1988-0