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Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice

Back pain is a leading cause of global disability and is strongly associated with intervertebral disc (IVD) degeneration (IDD). Hallmarks of IDD include progressive cell loss and matrix degradation. The Akt signaling pathway regulates cellularity and matrix production in IVDs and its inactivation is...

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Detalles Bibliográficos
Autores principales:	Zhang, Changli, Smith, Madeline P., Zhou, George K., Lai, Alon, Hoy, Robert C., Mroz, Victoria, Torre, Olivia M., Laudier, Damien M., Bradley, Elizabeth W., Westendorf, Jennifer J., Iatridis, James C., Illien-Jünger, Svenja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776553/ https://www.ncbi.nlm.nih.gov/pubmed/31582730 http://dx.doi.org/10.1038/s41419-019-1985-3

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