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Reduced mu opioid receptor availability in schizophrenia revealed with [(11)C]-carfentanil positron emission tomographic Imaging

Negative symptoms, such as amotivation and anhedonia, are a major cause of functional impairment in schizophrenia. There are currently no licensed treatments for negative symptoms, highlighting the need to understand the molecular mechanisms underlying them. Mu-opioid receptors (MOR) in the striatum...

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Detalles Bibliográficos
Autores principales:	Ashok, Abhishekh H., Myers, Jim, Reis Marques, Tiago, Rabiner, Eugenii A., Howes, Oliver D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776653/ https://www.ncbi.nlm.nih.gov/pubmed/31582737 http://dx.doi.org/10.1038/s41467-019-12366-4

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