Cargando…
Multi-input chemical control of protein dimerization for programming graded cellular responses
Chemical and optogenetic methods for post-translationally controlling protein function have enabled new discoveries and the engineering of synthetic cellular functions. However, most of these methods only confer single-input, single-output control. To increase the diversity of post-translational beh...
Autores principales: | Foight, Glenna Wink, Wang, Zhizhi, Wei, Cindy T., Greisen, Per, Warner, Katrina M., Cunningham-Bryant, Daniel, Park, Keunwan, Brunette, T. J., Sheffler, William, Baker, David, Maly, Dustin J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776690/ https://www.ncbi.nlm.nih.gov/pubmed/31501561 http://dx.doi.org/10.1038/s41587-019-0242-8 |
Ejemplares similares
-
Designed BH3 Peptides with High Affinity and Specificity
for Targeting Mcl-1 in Cells
por: Foight, Glenna Wink, et al.
Publicado: (2014) -
De novo design of a fluorescence-activating β-barrel
por: Dou, Jiayi, et al.
Publicado: (2018) -
Combinatorial protein dimerization enables precise multi-input synthetic computations
por: Bertschi, Adrian, et al.
Publicado: (2023) -
Light‐Induced Dimerization Approaches to Control Cellular Processes
por: Klewer, Laura, et al.
Publicado: (2019) -
Crystal structure and cellular functions of uPAR dimer
por: Yu, Shujuan, et al.
Publicado: (2022)