Precision mouse models with expanded tropism for human pathogens

A major limitation of current humanized mouse models is that they primarily enable the analysis of human-specific pathogens that infect hematopoietic cells. However, most human pathogens target other cell types, including epithelial, endothelial and mesenchymal cells. Here, we show that implantation...

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Detalles Bibliográficos
Autores principales: Wahl, Angela, De, Chandrav, Abad Fernandez, Maria, Lenarcic, Erik M., Xu, Yinyan, Cockrell, Adam S., Cleary, Rachel A., Johnson, Claire E., Schramm, Nathaniel J., Rank, Laura M., Newsome, Isabel G., Vincent, Heather A., Sanders, Wes, Aguilera-Sandoval, Christian R., Boone, Allison, Hildebrand, William H., Dayton, Paul A., Baric, Ralph S., Pickles, Raymond J., Braunstein, Miriam, Moorman, Nathaniel J., Goonetilleke, Nilu, Victor Garcia, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776695/
https://www.ncbi.nlm.nih.gov/pubmed/31451733
http://dx.doi.org/10.1038/s41587-019-0225-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776695/
https://www.ncbi.nlm.nih.gov/pubmed/31451733
http://dx.doi.org/10.1038/s41587-019-0225-9

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