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TDP2 negatively regulates axon regeneration by inducing SUMOylation of an Ets transcription factor

In Caenorhabditis elegans, the JNK MAP kinase (MAPK) pathway is important for axon regeneration. The JNK pathway is activated by a signaling cascade consisting of the growth factor SVH‐1 and its receptor tyrosine kinase SVH‐2. Expression of the svh‐2 gene is induced by axonal injury in a process inv...

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Detalles Bibliográficos
Autores principales:	Sakai, Yoshiki, Hanafusa, Hiroshi, Pastuhov, Strahil Iv, Shimizu, Tatsuhiro, Li, Chun, Hisamoto, Naoki, Matsumoto, Kunihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776894/ https://www.ncbi.nlm.nih.gov/pubmed/31393064 http://dx.doi.org/10.15252/embr.201847517

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