Targeting of early endosomes by autophagy facilitates EGFR recycling and signalling

Despite recently uncovered connections between autophagy and the endocytic pathway, the role of autophagy in regulating endosomal function remains incompletely understood. Here, we find that the ablation of autophagy‐essential players disrupts EGF‐induced endocytic trafficking of EGFR. Cells lacking...

Descripción completa

Detalles Bibliográficos
Autores principales: Fraser, Jane, Simpson, Joanne, Fontana, Rosa, Kishi‐Itakura, Chieko, Ktistakis, Nicholas T, Gammoh, Noor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776898/
https://www.ncbi.nlm.nih.gov/pubmed/31448519
http://dx.doi.org/10.15252/embr.201947734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776898/
https://www.ncbi.nlm.nih.gov/pubmed/31448519
http://dx.doi.org/10.15252/embr.201947734

Ejemplares similares