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Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against

Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to develop new...

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Autor principal: Krishna, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777023/
https://www.ncbi.nlm.nih.gov/pubmed/31581951
http://dx.doi.org/10.1186/s12936-019-2976-7
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author Krishna, Sanjeev
author_facet Krishna, Sanjeev
author_sort Krishna, Sanjeev
collection PubMed
description Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to develop new classes of anti-malarial drugs and not to make ‘triple combination therapies’ when there is already resistance to one or more proposed components.
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spelling pubmed-67770232019-10-07 Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against Krishna, Sanjeev Malar J Debate Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to develop new classes of anti-malarial drugs and not to make ‘triple combination therapies’ when there is already resistance to one or more proposed components. BioMed Central 2019-10-03 /pmc/articles/PMC6777023/ /pubmed/31581951 http://dx.doi.org/10.1186/s12936-019-2976-7 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Debate
Krishna, Sanjeev
Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_full Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_fullStr Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_full_unstemmed Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_short Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_sort triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
topic Debate
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777023/
https://www.ncbi.nlm.nih.gov/pubmed/31581951
http://dx.doi.org/10.1186/s12936-019-2976-7
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