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Alphavirus-based hepatitis C virus therapeutic vaccines: can universal helper epitopes enhance HCV-specific cytotoxic T lymphocyte responses?

BACKGROUND: Antigen-specific T cell immune responses play a pivotal role in resolving acute and chronic hepatitis C virus (HCV) infections. Currently, no prophylactic or therapeutic vaccines against HCV are available. We previously demonstrated the preclinical potency of therapeutic HCV vaccines bas...

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Detalles Bibliográficos
Autores principales:	Koutsoumpli, Georgia, Ip, Peng Peng, Schepel, Ilona, Hoogeboom, Baukje Nynke, Boerma, Annemarie, Daemen, Toos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777054/ https://www.ncbi.nlm.nih.gov/pubmed/31620673 http://dx.doi.org/10.1177/2515135519874677

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