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A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats

Objective The aim of this study was to explain a new technique for research on wound healing through extraction of mandibular lower incisors in Wistar rats. Materials and Methods Fifty Wistar rats were used from studies using the experimental animal to investigate the effects of wound healing drugs...

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Autor principal: Khoswanto, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Private Ltd. 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777148/
https://www.ncbi.nlm.nih.gov/pubmed/31466118
http://dx.doi.org/10.1055/s-0039-1694312
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author Khoswanto, Christian
author_facet Khoswanto, Christian
author_sort Khoswanto, Christian
collection PubMed
description Objective The aim of this study was to explain a new technique for research on wound healing through extraction of mandibular lower incisors in Wistar rats. Materials and Methods Fifty Wistar rats were used from studies using the experimental animal to investigate the effects of wound healing drugs on alveolar bone. The mandibular incisors of the Wistar rats were extracted using a special modified bein and special pulling pliers under general anesthesia. The tooth socket after extraction was closed using a 5.0 suture nylon needle. Results The results of this technique used in this extraction showed 2% incisor tooth fracture and 3% bleeding, and that all fractured teeth could be removed properly, and bleeding could be stopped after suturing. Conclusion The new techniques we use can be useful for research on mucosal and alveolar bone healing, specifically finding new types of drugs to accelerate wound healing after alveolar bone post extraction.
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spelling pubmed-67771482019-10-09 A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats Khoswanto, Christian Eur J Dent Objective The aim of this study was to explain a new technique for research on wound healing through extraction of mandibular lower incisors in Wistar rats. Materials and Methods Fifty Wistar rats were used from studies using the experimental animal to investigate the effects of wound healing drugs on alveolar bone. The mandibular incisors of the Wistar rats were extracted using a special modified bein and special pulling pliers under general anesthesia. The tooth socket after extraction was closed using a 5.0 suture nylon needle. Results The results of this technique used in this extraction showed 2% incisor tooth fracture and 3% bleeding, and that all fractured teeth could be removed properly, and bleeding could be stopped after suturing. Conclusion The new techniques we use can be useful for research on mucosal and alveolar bone healing, specifically finding new types of drugs to accelerate wound healing after alveolar bone post extraction. Thieme Medical and Scientific Publishers Private Ltd. 2019-05 2019-08-29 /pmc/articles/PMC6777148/ /pubmed/31466118 http://dx.doi.org/10.1055/s-0039-1694312 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Khoswanto, Christian
A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats
title A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats
title_full A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats
title_fullStr A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats
title_full_unstemmed A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats
title_short A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats
title_sort new technique for research on wound healing through extraction of mandibular lower incisors in wistar rats
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777148/
https://www.ncbi.nlm.nih.gov/pubmed/31466118
http://dx.doi.org/10.1055/s-0039-1694312
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