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A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats
Objective The aim of this study was to explain a new technique for research on wound healing through extraction of mandibular lower incisors in Wistar rats. Materials and Methods Fifty Wistar rats were used from studies using the experimental animal to investigate the effects of wound healing drugs...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical and Scientific Publishers Private Ltd.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777148/ https://www.ncbi.nlm.nih.gov/pubmed/31466118 http://dx.doi.org/10.1055/s-0039-1694312 |
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author | Khoswanto, Christian |
author_facet | Khoswanto, Christian |
author_sort | Khoswanto, Christian |
collection | PubMed |
description | Objective The aim of this study was to explain a new technique for research on wound healing through extraction of mandibular lower incisors in Wistar rats. Materials and Methods Fifty Wistar rats were used from studies using the experimental animal to investigate the effects of wound healing drugs on alveolar bone. The mandibular incisors of the Wistar rats were extracted using a special modified bein and special pulling pliers under general anesthesia. The tooth socket after extraction was closed using a 5.0 suture nylon needle. Results The results of this technique used in this extraction showed 2% incisor tooth fracture and 3% bleeding, and that all fractured teeth could be removed properly, and bleeding could be stopped after suturing. Conclusion The new techniques we use can be useful for research on mucosal and alveolar bone healing, specifically finding new types of drugs to accelerate wound healing after alveolar bone post extraction. |
format | Online Article Text |
id | pubmed-6777148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Thieme Medical and Scientific Publishers Private Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-67771482019-10-09 A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats Khoswanto, Christian Eur J Dent Objective The aim of this study was to explain a new technique for research on wound healing through extraction of mandibular lower incisors in Wistar rats. Materials and Methods Fifty Wistar rats were used from studies using the experimental animal to investigate the effects of wound healing drugs on alveolar bone. The mandibular incisors of the Wistar rats were extracted using a special modified bein and special pulling pliers under general anesthesia. The tooth socket after extraction was closed using a 5.0 suture nylon needle. Results The results of this technique used in this extraction showed 2% incisor tooth fracture and 3% bleeding, and that all fractured teeth could be removed properly, and bleeding could be stopped after suturing. Conclusion The new techniques we use can be useful for research on mucosal and alveolar bone healing, specifically finding new types of drugs to accelerate wound healing after alveolar bone post extraction. Thieme Medical and Scientific Publishers Private Ltd. 2019-05 2019-08-29 /pmc/articles/PMC6777148/ /pubmed/31466118 http://dx.doi.org/10.1055/s-0039-1694312 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Khoswanto, Christian A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats |
title | A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats |
title_full | A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats |
title_fullStr | A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats |
title_full_unstemmed | A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats |
title_short | A New Technique for Research on Wound Healing through Extraction of Mandibular Lower Incisors in Wistar Rats |
title_sort | new technique for research on wound healing through extraction of mandibular lower incisors in wistar rats |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777148/ https://www.ncbi.nlm.nih.gov/pubmed/31466118 http://dx.doi.org/10.1055/s-0039-1694312 |
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