Cargando…

MicroRNA-21-5p targeting PDCD4 suppresses apoptosis via regulating the PI3K/AKT/FOXO1 signaling pathway in tongue squamous cell carcinoma

The aim of the present study was to analyze the role of microRNA (miRNA)-21-5p in tongue squamous cell carcinoma (TSCC), predict the target gene of miR-21-5p and provide novel strategies for gene therapy in TSCC treatment. The expression levels of miRNA-21-5p in TSCC tissues were analyzed using reve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Changfu, Tong, Zhou, Tan, Jingyu, Xin, Zengxi, Wang, Zhiying, Tian, Luming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777222/ https://www.ncbi.nlm.nih.gov/pubmed/31602231 http://dx.doi.org/10.3892/etm.2019.7970

Ejemplares similares

MicroRNA-145-5p aggravates cell apoptosis and oxidative stress in tongue squamous cell carcinoma
por: Xin, Zengxi, et al.
Publicado: (2021)

Analysis of Treg/Th17 cells in patients with tongue squamous cell carcinoma
por: Liu, Changfu, et al.
Publicado: (2019)

MicroRNA-21 promotes neurite outgrowth by regulating PDCD4 in a rat model of spinal cord injury
por: Jiang, Yuqing, et al.
Publicado: (2017)

Anti-microRNA-132 causes sevoflurane-induced neuronal apoptosis via the PI3K/AKT/FOXO3a pathway
por: Dong, Ping, et al.
Publicado: (2018)

MicroRNA-21 plays an oncogenic role by targeting FOXO1 and activating the PI3K/AKT pathway in diffuse large B-cell lymphoma
por: Go, Heounjeong, et al.
Publicado: (2015)

The effects of HBXIP on the biological functions of tongue squamous cell carcinoma cells and correlation with PI3K/Akt
por: Meng, Xue, et al.
Publicado: (2020)

Ailanthone Inhibits Cell Proliferation in Tongue Squamous Cell Carcinoma via PI3K/AKT Pathway
por: Wang, Shuhan, et al.
Publicado: (2022)

MicroRNA-21 Plays Multiple Oncometabolic Roles in Colitis-Associated Carcinoma and Colorectal Cancer via the PI3K/AKT, STAT3, and PDCD4/TNF-α Signaling Pathways in Zebrafish
por: Lai, Chi-Yu, et al.
Publicado: (2021)

MicroRNA-21 and PDCD4 expression during in vitro oocyte maturation in pigs
por: Wright, Elane C., et al.
Publicado: (2016)

A Multicenter Study on Expressions of Vascular Endothelial Growth Factor, Matrix Metallopeptidase-9 and Tissue Inhibitor of Metalloproteinase-2 in Oral and Maxillofacial Squamous Cell Carcinoma
por: Li, Min, et al.
Publicado: (2014)

miR-21a inhibits decidual cell apoptosis by targeting Pdcd4
por: Li, Rong, et al.
Publicado: (2019)

FOXO1 Couples KGF and PI-3K/AKT Signaling to NKX2.1-Regulated Differentiation of Alveolar Epithelial Cells
por: Zhong, Qian, et al.
Publicado: (2022)

MicroRNA-552 Accelerates the Progression of Gastric Cancer by Targeting FOXO1 and Regulating PI3K/AKT Pathway
por: Zhao, Yuguo, et al.
Publicado: (2021)

Pdcd2l Promotes Palmitate-Induced Pancreatic Beta-Cell Apoptosis as a FoxO1 Target Gene
por: Yin, Ye, et al.
Publicado: (2016)

MicroRNA-21 Down-regulates Rb1 Expression by Targeting PDCD4 in Retinoblastoma
por: Shen, Fengmei, et al.
Publicado: (2014)

miR-21 attenuates contrast-induced renal cell apoptosis by targeting PDCD4
por: Wang, Kun, et al.
Publicado: (2017)

MicroRNA-150 inhibitors enhance cell apoptosis of melanoma by targeting PDCD4
por: Wan, Jianji, et al.
Publicado: (2018)

Circulating microRNA-194 regulates human melanoma cells via PI3K/AKT/FoxO3a and p53/p21 signaling pathway
por: Bai, Ming, et al.
Publicado: (2017)

MicroRNA-766 Promotes The Proliferation, Migration And Invasion, And Inhibits The Apoptosis Of Cutaneous Squamous Cell Carcinoma Cells By Targeting PDCD5
por: Liu, Pengyu, et al.
Publicado: (2020)

Eugenol-Induced Autophagy and Apoptosis in Breast Cancer Cells via PI3K/AKT/FOXO3a Pathway Inhibition
por: Abdullah, Mashan L., et al.
Publicado: (2021)

MicroRNA-21 Contributes to Cutaneous Squamous Cell Carcinoma Progression via Mediating TIMP3/PI3K/AKT Signaling Axis
por: Yin, Shuhong, et al.
Publicado: (2021)

Silencing of SPP1 Suppresses Progression of Tongue Cancer by Mediating the PI3K/Akt Signaling Pathway
por: Zhang, Qiaoli, et al.
Publicado: (2020)

Circular RNA ITCH Suppresses Cell Proliferation but Induces Apoptosis in Oral Squamous Cell Carcinoma by Regulating miR-421/PDCD4 Axis
por: Hao, Chunbo, et al.
Publicado: (2020)

Reduced PDCD4 Expression Promotes Cell Growth Through PI3K/Akt Signaling in Non-Small Cell Lung Cancer
por: Zhen, Yan, et al.
Publicado: (2016)

MicroRNA-21 Contributes to Cutaneous Squamous Cell Carcinoma Progression via Mediating TIMP3/PI3K/AKT Signaling Axis [Retraction]
Publicado: (2023)

microRNA-199a-3p inhibits hepatic apoptosis and hepatocarcinogenesis by targeting PDCD4
por: Li, Zhenyang, et al.
Publicado: (2020)

Long non-coding RNA CASC2 serves as a ceRNA of microRNA-21 to promote PDCD4 expression in oral squamous cell carcinoma
por: Pan, Lina, et al.
Publicado: (2019)

Eldecalcitol prevents muscle loss by suppressing PI3K/AKT/FOXOs pathway in orchiectomized mice
por: Zhang, Haichao, et al.
Publicado: (2022)

IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways
por: Duan, Shiyu, et al.
Publicado: (2018)

Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways
por: Cao, Jinlin, et al.
Publicado: (2018)

The PI3K/AKT Pathway and FOXO3a Transcription Factor Mediate High Glucose-Induced Apoptosis in Neonatal Rat Ventricular Myocytes
por: Bao, Weiguo, et al.
Publicado: (2014)

Banxia Xiexin Decoction Ameliorates t-BHP-Induced Apoptosis in Pancreatic Beta Cells by Activating the PI3K/AKT/FOXO1 Signaling Pathway
por: Du, Li-juan, et al.
Publicado: (2020)

Curcumin alleviates oxidative stress and inhibits apoptosis in diabetic cardiomyopathy via Sirt1‐Foxo1 and PI3K‐Akt signalling pathways
por: Ren, Bin‐cheng, et al.
Publicado: (2020)

Trim32 reduces PI3K–Akt–FoxO signaling in muscle atrophy by promoting plakoglobin–PI3K dissociation
por: Cohen, Shenhav, et al.
Publicado: (2014)

CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy
por: Zhao, Chen, et al.
Publicado: (2022)

MicroRNA‐21 induces 5‐fluorouracil resistance in human pancreatic cancer cells by regulating PTEN and PDCD4
por: Wei, Xueju, et al.
Publicado: (2016)

Role of microRNA-21 in radiosensitivity in non-small cell lung cancer cells by targeting PDCD4 gene
por: Jiang, Li-Peng, et al.
Publicado: (2017)

Asiatic acid inhibits proliferation, migration and induces apoptosis by regulating Pdcd4 via the PI3K/Akt/mTOR/p70S6K signaling pathway in human colon carcinoma cells
por: Hao, Yajuan, et al.
Publicado: (2018)

Piceatannol Suppresses the Proliferation and Induced Apoptosis of Osteosarcoma Cells Through PI3K/AKT/mTOR Pathway
por: Wang, Bin, et al.
Publicado: (2020)

MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7
por: Feng, Cuijuan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9otqplm7ofq5cajgo31j0cj8t3