Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer

IMPORTANCE: Radiation therapy for breast cancer is associated with increased risk of a second primary contralateral breast cancer, but the genetic factors modifying this association are not well understood. OBJECTIVE: To determine whether a genetic risk score comprising single nucleotide polymorphis...

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Detalles Bibliográficos
Autores principales: Watt, Gordon P., Reiner, Anne S., Smith, Susan A., Stram, Daniel O., Capanu, Marinela, Malone, Kathleen E., Lynch, Charles F., John, Esther M., Knight, Julia A., Mellemkjær, Lene, Bernstein, Leslie, Brooks, Jennifer D., Woods, Meghan, Liang, Xiaolin, Haile, Robert W., Riaz, Nadeem, Conti, David V., Robson, Mark, Duggan, David, Boice, John D., Shore, Roy E., Tischkowitz, Marc, Orlow, Irene, Thomas, Duncan C., Concannon, Patrick, Bernstein, Jonine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777239/
https://www.ncbi.nlm.nih.gov/pubmed/31560388
http://dx.doi.org/10.1001/jamanetworkopen.2019.12259

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