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Large-Scale Molecular Evolutionary Analysis Uncovers a Variety of Polynucleotide Kinase Clp1 Family Proteins in the Three Domains of Life

Clp1, a polyribonucleotide 5′-hydroxyl kinase in eukaryotes, is involved in pretRNA splicing and mRNA 3′-end formation. Enzymes similar in amino acid sequence to Clp1, Nol9, and Grc3, are present in some eukaryotes and are involved in prerRNA processing. However, our knowledge of how these Clp1 fami...

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Detalles Bibliográficos
Autores principales: Saito, Motofumi, Sato, Asako, Nagata, Shohei, Tamaki, Satoshi, Tomita, Masaru, Suzuki, Haruo, Kanai, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777427/
https://www.ncbi.nlm.nih.gov/pubmed/31513263
http://dx.doi.org/10.1093/gbe/evz195