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DiOHF Protects Against Doxorubicin-Induced Cardiotoxicity Through ERK1 Signaling Pathway

Doxorubicin (DOX) is an effective anticancer agent. Its clinical use is, however, limited due to its detrimental side effects, especially the cardiotoxicity caused by ROS, mitochondrial dysfunction and apoptosis. 3’,4’-dihydroxyflavonol (DiOHF) is a recently developed potent synthetic flavonoid whic...

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Detalles Bibliográficos
Autores principales: Chang, Danqi, Li, Hang, Qian, Cheng, Wang, Yanggan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777440/
https://www.ncbi.nlm.nih.gov/pubmed/31611788
http://dx.doi.org/10.3389/fphar.2019.01081

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