Cargando…

Resistance To First-Line Antituberculosis Drugs And Prevalence Of pncA Mutations In Clinical Isolates Of Mycobacterium tuberculosis From Zunyi, Guizhou Province Of China

BACKGROUND: China is one of the high-burden countries for multidrug-resistant tuberculosis (MDR-TB), and pyrazinamide is one of the anti-TB drugs used for the shorter MDR-TB treatment regimen. The aim of this study was to determine the correlation between pncA gene mutations and resistance to four f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Zhimin, Lan, Yuanbo, Chen, Ling, Xiang, Min, Peng, Zhiyuan, Zhang, Jianyong, Zhang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777635/ https://www.ncbi.nlm.nih.gov/pubmed/31686870 http://dx.doi.org/10.2147/IDR.S222943

Ejemplares similares

Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Korea.
por: Lee, K. W., et al.
Publicado: (2001)

pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea
por: Park, Soon Kew, et al.
Publicado: (2001)

Pyrazinamide Resistance and pncA Mutation Profiles in Multidrug Resistant Mycobacterium Tuberculosis
por: Shi, Dawei, et al.
Publicado: (2022)

pncA Mutations in the Specimens from Extrapulmonary Tuberculosis
por: Lee, Jaechun, et al.
Publicado: (2012)

Novel Mutations in pncA Gene of Pyrazinamide Resistant Clinical Isolates of Mycobacterium tuberculosis
por: Kahbazi, Manijeh, et al.
Publicado: (2018)

Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan
por: Chiu, Yu-Chi, et al.
Publicado: (2011)

Pyrazinamide Susceptibility and pncA Mutation Profiles of Mycobacterium tuberculosis among Multidrug-Resistant Tuberculosis Patients in Bangladesh
por: Rahman, Arfatur, et al.
Publicado: (2017)

Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis
por: Baddam, Ramani, et al.
Publicado: (2018)

Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan
por: khan, Muhammad Tahir, et al.
Publicado: (2019)

Detection of Mutations in pncA in Mycobacterium tuberculosis Clinical Isolates from Nepal in Association with Pyrazinamide Resistance
por: Shrestha, Dipti, et al.
Publicado: (2022)

pncA Large Deletion is the Characteristic of Pyrazinamide-Resistant Mycobacterium tuberculosis belonging to the East Asian Lineage
por: Kim, Na Yung, et al.
Publicado: (2023)

Characterization of pncA Mutations and Prediction of PZA Resistance in Mycobacterium tuberculosis Clinical Isolates From Chongqing, China
por: Li, Kun, et al.
Publicado: (2021)

Structure guided prediction of Pyrazinamide resistance mutations in pncA
por: Karmakar, Malancha, et al.
Publicado: (2020)

Pyrazinamide resistance of novel mutations in pncA and their dynamic behavior
por: Ali, Arif, et al.
Publicado: (2020)

Author Correction: Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis
por: Baddam, Ramani, et al.
Publicado: (2018)

A computational perspective on the dynamic behaviour of recurrent drug resistance mutations in the pncA gene from Mycobacterium tuberculosis
por: Khan, Taimoor, et al.
Publicado: (2021)

A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide
por: Yadon, Adam N., et al.
Publicado: (2017)

High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda
por: Naluyange, Resty, et al.
Publicado: (2020)

1696 Total-deletion mutation of pncA as a new mechanism of pyrazinamide resistance in Mycobacterium tuberculosis - The first report from Japan
por: Kobayashi, Masahiro, et al.
Publicado: (2014)

pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia
por: Allana, Salim, et al.
Publicado: (2017)

Insights Into Mutations Induced Conformational Changes and Rearrangement of Fe(2+) Ion in pncA Gene of Mycobacterium tuberculosis to Decipher the Mechanism of Resistance to Pyrazinamide
por: Nangraj, Asma Sindhoo, et al.
Publicado: (2021)

Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia
por: Sengstake, Sarah, et al.
Publicado: (2017)

Drug resistance profiles and trends in drug-resistant tuberculosis at a major hospital in Guizhou Province of China
por: Lan, Yuanbo, et al.
Publicado: (2019)

Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection
por: Dudley, Matthew Z., et al.
Publicado: (2016)

Gibbs Free Energy Calculation of Mutation in PncA and RpsA Associated With Pyrazinamide Resistance
por: Khan, Muhammad Tahir, et al.
Publicado: (2020)

Structural Dynamics Behind Clinical Mutants of PncA-Asp12Ala, Pro54Leu, and His57Pro of Mycobacterium tuberculosis Associated With Pyrazinamide Resistance
por: Mehmood, Aamir, et al.
Publicado: (2019)

Whole-Genome Sequences of Two Clinical Isolates of Extensively Drug-Resistant Mycobacterium tuberculosis from Zunyi, China
por: Chen, Ling, et al.
Publicado: (2014)

Bacterial PncA improves diet-induced NAFLD in mice by enabling the transition from nicotinamide to nicotinic acid
por: Feng, Shengyu, et al.
Publicado: (2023)

Rapid Pyrazinamide Drug Susceptibility Testing using a Closed-Tube PCR Assay of the Entire pncA gene
por: Whitfield, Michael G., et al.
Publicado: (2020)

PncAgene expression and prediction factors on pyrazinamide resistance in Mycobacterium tuberculosis
por: Untiveros, Katherine Lozano, et al.
Publicado: (2014)

Mycobacterium tuberculosis resistance to antituberculosis drugs in Mozambique,
por: Pires, Germano Manuel, et al.
Publicado: (2014)

Evaluation of PCR pncA-restriction fragment length polymorphism and PCR amplification of genomic regions of difference for the identification of M. bovis strains in lymph nodes cultures
por: Bouzouita, Imen, et al.
Publicado: (2021)

Upward trends in new, rifampicin-resistant and concurrent extrapulmonary tuberculosis cases in northern Guizhou Province of China
por: Chen, Ling, et al.
Publicado: (2021)

Investigation of 3-year inpatient TB cases in Zunyi, China: Increased TB burden but improved bacteriological diagnosis
por: Chen, Ling, et al.
Publicado: (2022)

Pattern of drug resistance of Mycobacterium tuberculosis clinical isolates to first-line antituberculosis drugs in pulmonary cases
por: Kalo, Deepika, et al.
Publicado: (2015)

Analysis of Multigene Mutations in Lung Adenocarcinoma in Zunyi
por: Ma, Qingqing, et al.
Publicado: (2021)

Analysis of Treatment and Prognosis of 863 Patients with Spinal Tuberculosis in Guizhou Province
por: Cao, Guangru, et al.
Publicado: (2018)

Mycobacterium tuberculosis Specific CD8(+) T Cells Rapidly Decline with Antituberculosis Treatment
por: Nyendak, Melissa R., et al.
Publicado: (2013)

Mycobacterium tuberculosisβ-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs
por: Aspatwar, Ashok, et al.
Publicado: (2019)

The Impact of COVID-19 Epidemic on Tuberculosis Reports Among Students — Guizhou Province, China, 2020
por: He, Yuying, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_008q1tbljlquiihh8n31ug992i