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L-3,3’,5-triiodothyronine and pregnenolone sulfate inhibit Torpedo nicotinic acetylcholine receptors

The nicotinic acetylcholine receptor (nAChR) is an excitatory pentameric ligand-gated ion channel (pLGIC), homologous to the inhibitory γ-aminobutyric acid (GABA) type A receptor targeted by pharmaceuticals and endogenous sedatives. Activation of the GABA(A) receptor by the neurosteroid allopregnano...

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Detalles Bibliográficos
Autores principales:	Moffett, Steven X., Klein, Eric A., Brannigan, Grace, Martin, Joseph V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777777/ https://www.ncbi.nlm.nih.gov/pubmed/31584962 http://dx.doi.org/10.1371/journal.pone.0223272

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