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Deletion of PTPN22 improves effector and memory CD8(+) T cell responses to tumors
Adoptive T cell therapy (ACT) has been established as an efficacious methodology for the treatment of cancer. Identifying targets to enhance the antigen recognition, functional capacity, and longevity of T cells has the potential to broaden the applicability of these approaches in the clinic. We pre...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777814/ https://www.ncbi.nlm.nih.gov/pubmed/31335326 http://dx.doi.org/10.1172/jci.insight.127847 |