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Deletion of PTPN22 improves effector and memory CD8(+) T cell responses to tumors

Adoptive T cell therapy (ACT) has been established as an efficacious methodology for the treatment of cancer. Identifying targets to enhance the antigen recognition, functional capacity, and longevity of T cells has the potential to broaden the applicability of these approaches in the clinic. We pre...

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Detalles Bibliográficos
Autores principales:	Brownlie, Rebecca J., Wright, David, Zamoyska, Rose, Salmond, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777814/ https://www.ncbi.nlm.nih.gov/pubmed/31335326 http://dx.doi.org/10.1172/jci.insight.127847

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