Cargando…
MITF controls the TCA cycle to modulate the melanoma hypoxia response
In response to the dynamic intra‐tumor microenvironment, melanoma cells adopt distinct phenotypic states associated with differential expression of the microphthalmia‐associated transcription factor (MITF). The response to hypoxia is driven by hypoxia‐inducible transcription factors (HIFs) that repr...
Autores principales: | Louphrasitthiphol, Pakavarin, Ledaki, Ioanna, Chauhan, Jagat, Falletta, Paola, Siddaway, Robert, Buffa, Francesca M., Mole, David R., Soga, Tomoyoshi, Goding, Colin R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777998/ https://www.ncbi.nlm.nih.gov/pubmed/31207090 http://dx.doi.org/10.1111/pcmr.12802 |
Ejemplares similares
-
The MITF regulatory network in melanoma
por: Chauhan, Jagat S., et al.
Publicado: (2022) -
The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor
por: Coe, Elizabeth A., et al.
Publicado: (2019) -
TBX2 controls a proproliferative gene expression program in melanoma
por: Lu, Sizhu, et al.
Publicado: (2021) -
Acetylation reprograms MITF target selectivity and residence time
por: Louphrasitthiphol, Pakavarin, et al.
Publicado: (2023) -
MITF—the first 25 years
por: Goding, Colin R., et al.
Publicado: (2019)