Mouse embryo geometry drives formation of robust signaling gradients through receptor localization

Morphogen signals are essential for cell fate specification during embryogenesis. Some receptors that sense these morphogens are known to localize to only the apical or basolateral membrane of polarized cell lines in vitro. How such localization affects morphogen sensing and patterning in the develo...

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Detalles Bibliográficos
Autores principales: Zhang, Zhechun, Zwick, Steven, Loew, Ethan, Grimley, Joshua S., Ramanathan, Sharad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778081/
https://www.ncbi.nlm.nih.gov/pubmed/31586065
http://dx.doi.org/10.1038/s41467-019-12533-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778081/
https://www.ncbi.nlm.nih.gov/pubmed/31586065
http://dx.doi.org/10.1038/s41467-019-12533-7

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