Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes

Arctigenin (ATG) is a major component of Fructus Arctii, a traditional herbal remedy that reduced proteinuria in diabetic patients. However, whether ATG specifically provides renoprotection in DKD is not known. Here we report that ATG administration is sufficient to attenuate proteinuria and podocyt...

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Detalles Bibliográficos
Autores principales: Zhong, Yifei, Lee, Kyung, Deng, Yueyi, Ma, Yueming, Chen, Yiping, Li, Xueling, Wei, Chengguo, Yang, Shumin, Wang, Tianming, Wong, Nicholas J., Muwonge, Alecia N., Azeloglu, Evren U., Zhang, Weijia, Das, Bhaskar, He, John Cijiang, Liu, Ruijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778111/
https://www.ncbi.nlm.nih.gov/pubmed/31586053
http://dx.doi.org/10.1038/s41467-019-12433-w

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