Association between genetic polymorphisms of NRF2, KEAP1, MAFF, MAFK and anti-tuberculosis drug-induced liver injury: a nested case-control study

Reactive metabolites of anti-tuberculosis (anti-TB) drugs can result in excessive reactive oxygen species (ROS), which are responsible for drug-induced liver injury. The nuclear factor erythroid 2-related factor 2 (Nrf2) - antioxidant response elements (ARE) (Nrf2-ARE) signaling pathway plays a cruc...

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Detalles Bibliográficos
Autores principales: Chen, Shixian, Pan, Hongqiu, Chen, Yongzhong, Lu, Lihuan, He, Xiaomin, Chen, Hongbo, Chen, Ru, Zhan, Siyan, Tang, Shaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778130/
https://www.ncbi.nlm.nih.gov/pubmed/31586142
http://dx.doi.org/10.1038/s41598-019-50706-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778130/
https://www.ncbi.nlm.nih.gov/pubmed/31586142
http://dx.doi.org/10.1038/s41598-019-50706-y

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