Genetic modification of primary human B cells to model high-grade lymphoma

Sequencing studies of diffuse large B cell lymphoma (DLBCL) have identified hundreds of recurrently altered genes. However, it remains largely unknown whether and how these mutations may contribute to lymphomagenesis, either individually or in combination. Existing strategies to address this problem...

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Detalles Bibliográficos
Autores principales: Caeser, Rebecca, Di Re, Miriam, Krupka, Joanna A., Gao, Jie, Lara-Chica, Maribel, Dias, João M. L., Cooke, Susanna L., Fenner, Rachel, Usheva, Zelvera, Runge, Hendrik F. P., Beer, Philip A., Eldaly, Hesham, Pak, Hyo-Kyung, Park, Chan-Sik, Vassiliou, George S., Huntly, Brian J. P., Mupo, Annalisa, Bashford-Rogers, Rachael J. M., Hodson, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778131/
https://www.ncbi.nlm.nih.gov/pubmed/31586074
http://dx.doi.org/10.1038/s41467-019-12494-x

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