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Identification of the Sex of Pre-implantation Mouse Embryos Using a Marked Y Chromosome and CRISPR/Cas9

Although numerous attempts have been made to alter the sex ratio of the progeny of mammals, the limitations of current technologies have prevented their widespread use in farm animals. The presence or absence of a Y chromosome determines whether a mammalian embryo develops as a male or female, and n...

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Detalles Bibliográficos
Autores principales: Zhao, Xiuling, Wei, Wei, Pan, Hong, Nie, Junyu, Chen, Dongrong, Zhang, Pengfei, Chen, Fumei, Fu, Qiang, Zuo, Erwei, Lu, Yangqing, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778187/
https://www.ncbi.nlm.nih.gov/pubmed/31586114
http://dx.doi.org/10.1038/s41598-019-50731-x

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