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Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes

A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected individuals. This occludes blood flow, leads to inflammation, and increases parasitemia by reducing spleen-mediated clearance of...

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Detalles Bibliográficos
Autores principales:	Lennartz, Frank, Smith, Cameron, Craig, Alister G., Higgins, Matthew K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778195/ https://www.ncbi.nlm.nih.gov/pubmed/31527263 http://dx.doi.org/10.1073/pnas.1911900116

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