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Apatinib induces 3‐hydroxybutyric acid production in the liver of mice by peroxisome proliferator‐activated receptor α activation to aid its antitumor effect

Apatinib, an antiangiogenic agent, shows efficient antitumor activity in a broad range of malignancies. Considering tumor is a type of metabolic disease, we investigated the metabolomics changes in serum and tumor after apatinib treatment and the molecular mechanism of characteristic changes associa...

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Detalles Bibliográficos
Autores principales:	Feng, Siqi, Wang, Huan, Wang, Ying, Sun, Runbin, Xie, Yuan, Zhou, Zhu, Wang, Hong, Aa, Jiye, Zhou, Fang, Wang, Guangji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778632/ https://www.ncbi.nlm.nih.gov/pubmed/31429167 http://dx.doi.org/10.1111/cas.14168

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