Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib‐sensitive and ‐resistant multiple myeloma cells

p97/VCP is an endoplasmic reticulum (ER)‐associated protein that belongs to the AAA (ATPases associated with diverse cellular activities) ATPase family. It has a variety of cellular functions including ER‐associated protein degradation, autophagy, and aggresome formation. Recent studies have shown e...

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Detalles Bibliográficos
Autores principales: Nishimura, Nao, Radwan, Mohamed O., Amano, Masayuki, Endo, Shinya, Fujii, Eri, Hayashi, Hironori, Ueno, Shikiko, Ueno, Niina, Tatetsu, Hiro, Hata, Hiroyuki, Okamoto, Yoshinari, Otsuka, Masami, Mitsuya, Hiroaki, Matsuoka, Masao, Okuno, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778635/
https://www.ncbi.nlm.nih.gov/pubmed/31368616
http://dx.doi.org/10.1111/cas.14154

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